کنفرانس مهندسی برق ایران

صفحه اصلی / سی و سومین کنفرانس بین المللی مهندسی برق

Comparative Analysis of flash-Visually Evoked Potential Based on Recorded Signal Powers from Rat’s Occipital Cortex

نویسندگان :

Masoud Poostchi Avval¹ Ehsan Naeemi² Mohammad Maymandi Nejad³ Ali Moghimi⁴

1- Department of Electrical Engineering, Faculty of Engineering, Ferdowsi University of Mashhad 2- Department of Electrical Engineering, Faculty of Engineering, Ferdowsi University of Mashhad 3- professor, Department of Electrical Engineering, Faculty of Engineering, Ferdowsi University of Mashhad 4- professor of Rayan Research Center for Neuroscience & Behavior, Department of Biology, Faculty of Sciences, Ferdowsi University of Mashhad

کلمات کلیدی :

Ipsi-lateral hemisphere،Contra-lateral hemisphere،Colored light،VEP signal power،Rat،Occipital cortex

چکیده :

Purpose Visually Evoked Potentials (VEPs) have many applications, such as clinical, biomedical engineering and, neuroscience. Generally, these signals are usually analyzed based on multiple variables such as amplitude and time characteristics. These signals are divided into two main types: Flash and pattern VEPs. Because of the intrinsic variability of analytic parameters of VEPs, amplitude, and time, interpreting this kind of EPs is sometimes more sophisticated due to the abnormal shape of some VEPs. Hence we suggested a new parameter, “power”, to create a better comparison between VEPs. This variable does not depend on VEP shape and can summarize the cortex response in a single simple and reliable value. The proposed parameter was used to express differences between potentials recorded from the occipital cortexes of rats under different color stimulations. Methods In this research, six adult Wistar rats were studied. In each case, two electrodes (active electrodes) in the posterior scalp (occipital) at both hemispheres, and one reference electrode was fixed at lambda. Photic stimulations (blue, green, white, and red) were repeated for 100 trials (for each eye). Colored Flash VEPs recorded from both hemispheres were studied and compared based on their powers. Results Based on this proposal, experiments showed the contra-lateral hemisphere had 4.15 times more VEP power than ipsi-lateral hemisphere (P < 0.05). Also, this research proves that blue, green, and white light lead to 2.42, 2.36 and 2.35 stronger VEP power than the red color light, respectively (P < 0.05). Conclusion Investigations show that VEPs power can be a reliable single concise tool to represent the VEP. It describes correctly the difference between different responses of color stimulation and neuroanatomical projections from each retina to the contra-ipsi-lateral occipital in rats.